Publications

1. Okano S, Lan L, Caldecott KW, Mori T, Yasui A. “Spatial and temporal cellular responses to single-strand breaks in human cells.” Mol. Cell. Biol. (2003) Jun; 23(11): 3974-81. PMID: 12748298

2. Lan L, Hayashi T, Rabeya RM, Nakajima S, Kanno S, Takao M, Matsunaga T, Yoshino M, Ichikawa M, Riele H, Tsuchiya S, Tanaka K, Yasui A. “Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum (II) in mammalian cells.” DNA Repair (Amst). (2004) Feb 3; 3(2): 135-43. PMID: 14706347

3. Nakajima S, Lan L, Kanno S, Takao M, Yamamoto K, Eker AP, Yasui A. “UV light-induced DNA damage and tolerance for the survival of nucleotide excision repair-deficient human cells.” J. Biol. Chem. (2004) Nov 5; 279(45): 46674-7. PMID: 15342631

4. Lan L, Nakajima S, Oohata Y, Takao M, Okano S, Masutani M, Wilson SH, Yasui A. “In situ analysis of repair processes for oxidative DNA damage in mammalian cells.” Proc. Natl. Acad. Sci. U S A. (2004) Sep 21; 101(38):13738-43. PMID: 15365186

5. Okano S, Lan L, Tomkinson AE, Yasui A. “Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells.” Nucleic Acids Res. (2005) Jan 14; 33(1): 422-9. PMID: 15653642

6. Wilson TM, Vaisman A, Martomo SA, Sullivan P, Lan L, Hanaoka F, Yasui A, Woodgate R, Gearhart PJ. “MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes.” J. Exp. Med. (2005) Feb 21; 201(4): 637-45. PMID: 15710654
7. Braithwaite EK, Kedar PS, Lan L, Polosina YY, Asagoshi K, Poltoratsky VP, Horton JK, Miller H, Teebor GW, Yasui A, Wilson SH. “DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair.” J. Biol. Chem. (2005) Sep 9; 280(36): 31641-7. PMID: 16002405

8. Lan L, Nakajima S, Komatsu K, Nussenzweig A, Shimamoto A, Oshima J, Yasui A. “Accumulation of Werner protein at DNA double-strand breaks in human cells.” J. Cell Sci. (2005) Sep 15; 118(Pt 18): 4153-62. PMID: 16141234

9. Karmakar P, Seki M, Kanamori M, Hashiguchi K, Ohtsuki M, Murata E, Inoue E, Tada S, Lan L, Yasui A, Enomoto T. “BLM is an early responder to DNA double-strand breaks.” Biochem. Biophys. Res. Commun. (2006) Sep 15; 348(1): 62-9. PMID: 16876111
10. Nakajima S, Lan L, Kanno S, Usami N, Kobayashi K, Mori M, Shiomi T, Yasui A. “Replication-dependent and -independent responses of RAD18 to DNA damage in human cells.” J. Biol. Chem. (2006) Nov 10; 281(45): 34687-95. PMID: 16980296

11. Yoshimura M, Kohzaki M, Nakamura J, Asagoshi K, Sonoda E, Hou E, Prasad R, Wilson SH, Tano K, Yasui A, Lan L, Seki M, Wood RD, Arakawa H, Buerstedde JM, Hochegger H, Okada T, Hiraoka M, Takeda S. “Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage.” Mol. Cell. (2006) Oct 6; 24(1): 115-25. PMID: 17018297

12. Saberi A, Hochegger H, Szuts D, Lan L, Yasui A, Sale JE, Taniguchi Y, Murakawa Y, Zeng W, Yokomori K, Helleday T, Teraoka H, Arakawa H, Buerstedde JM, Takeda S. “RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair.” Mol. Cell. Biol. (2007) Apr; 27(7): 2562-71. PMID: 17242200

13. Hirano M, Yamamoto A, Mori T, Lan L, Iwamoto TA, Aoki M, Shimada K, Furiya Y, Kariya S, Asai H, Yasui A, Nishiwaki T, Imoto K, Kobayashi N, Kiriyama T, Nagata T, Konishi N, Itoyama Y, Ueno S. “DNA single-strand break repair is impaired in aprataxin-related ataxia.” Ann. Neurol. (2007) Feb; 61(2): 162-74. PMID: 17315206

14. Kanno S, Kuzuoka H, Sasao S, Hong Z, Lan L, Nakajima S, Yasui A. “A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.” EMBO J. (2007) Apr 18; 26(8):2094-103. PMID: 17396150

15. Kamath-Loeb AS, Lan L, Nakajima S, Yasui A, Loeb LA. “Werner syndrome protein interacts functionally with translesion DNA polymerases.” Proc. Natl. Acad. Sci. USA. (2007) Jun 19; 104(25): 10394-9. PMID: 17563354; PMCID: PMC1965524

16. Hong Z, Jiang J, Lan L, Nakajima S, Kanno S, Koseki H, and Yasui A. “A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell.” Nucleic Acids Res. (2008) 36, 2939-2947, PMID: 18385154 PMCID: PMC2396414

17. Hong Z, Jiang J, Hashiguchi K, Hoshi M, Lan L, and Yasui A, “Recruitment of mismatch repair proteins to the site of DNA damage in human cells.” J. Cell Sci. (2008) Oct 1; 121(Pt 19): 3146-54 PMID: 18765568

18. Wei L, Lan L, Hong Z, Yasui A, Ishioka C, Chiba N. “Rapid recruitment of BRCA1 to DNA double-strand breaks is dependent on its association with Ku80.” Mol. Cell. Biol. (2008) Dec; 28(24): 7380-93. PMID: 18936166; PMCID: PMC2593434

19. Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH. “DNA polymerase beta-dependent long patch base excision repair in living cells.” DNA Repair (Amst). (2010) Feb 4; 9(2): 109-19. PMID: 20006562 PMCID: PMC2819632

20. Horibata K, Saijo M, Bay MN, Lan L, Kuraoka I, Brooks PJ, Honma M, Nohmi T, Yasui A, Tanaka K. “Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex.” Genes Cells. (2010) Dec 9. 16, 101-14 PMID: 21143350

21. Lan L, Ui A, Nakajima S, Hatakeyama K, Hoshi M, Watanabe R, Janicki SM, Ogiwara H, Kohno T, Kanno S and Yasui A. “The ACF1 complex is required for DNA double-strand break repair in human cells.” Mol. Cell. (2010) Dec 22; 40(6): 976-87. PMID: 21172662

22. Wei, L. Lan L, Yasui A, Tanaka K, Saijo M, Matsuzawa A, Kashiwagi R, Maseki E, Hu Y, Parvin JD, Ishioka C, and Chiba N. “BRCA1 contributes to transcription-coupled repair of DNA damage through polyubiquitination and degradation of Cockayne syndrome B protein.” Cancer Sci. (2011),Oct.102(10): 1840-7 PMID: 21756275

23. Lan L, Nakajima S, Kapetanaki MG, Hsieh CL, Fagerburg M, Thickman K, Rodriguez-Collazo P, Leuba SH, Levine AS, Rapic-Otrin V. Monoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligase. J. Biol. Chem. (2012) 287(15): 12036-49 PMID: 22334663; PMCID: PMC3320950

24. Wei L, Nakajima S, Hsieh CL, Kanno S, Masutani M, Levine AS, Yasui A, Lan L (corresponding author) “Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitination after degradation of poly (ADP) ribose.” J. Cell Sci. (2013) Oct 1; 126 (Pt 19): 4414-4423. PMID: 23868975

25. Xu L, Chen YC, NakajimaS,Chong J, Wang L, Lan L, Zhang C, and Wang D. “A Chemical Probe Targets DNA 5-Formylcytosine Sites and Inhibits TDG Excision, Polymerases Bypass, and Gene Expression.” Chemical Science (2014); 5: 567-574. doi: 10.1039/C3SC51849C

26. Benitez A, Yuan F, Nakajima S, Wei L, Qian L, Myers R, Hu J, Lan L, Zhang Y. “Damage-Dependent Regulation of MUS81-EME1 by Fanconi Anemia Complementation Group A Protein.” Nucleic Acid Res. (2014); 2014 Feb; 42(3):1671-83. PMID: 24170812

27. Satoshi Nakajima, Li Lan (co-corresponding), Leizhen Wei, Ching-Lung Hsieh, Vesna Rapic-Otrin, Akira Yasui, Arthur S. Levine Ubiquitin-specific protease 5 is required for the efficient repair of DNA double-strand breaks. Plos one (2014); Jan 14; 9(1): e84899 PMID: 24454762

28. Li Lan (corresponding author), Satoshi Nakajima, Leizhen Wei, Luxi Sun, Ching-Lung Hsieh, Robert W. Sobol, Marcel Bruchez, Bennett Van Houten, Akira Yasui, Arthur S. Levine. Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin. Nucleic Acid Res. (2014); 2014 Feb 1; 42(4): 2330-45. PMID: 24293652